2,4,6-Trifluorophenylboronic Acid CAS 182482-25-3 Supplier and Procurement Guide

If you are sourcing 2,4,6-Trifluorophenylboronic acid, CAS 182482-25-3, I recommend starting with identity confirmation, intended reaction use, required quality level, and documentation expectations. This compound is an organoboronic acid used primarily as a building block in synthetic chemistry, including palladium-catalyzed cross-coupling research and pharmaceutical or agrochemical intermediate development. At Maison Chemical, I help buyers evaluate the correct specification, packaging, documentation, and supply arrangement before they place an order.

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Who This Procurement Guide Is For

This guide is intended for research chemists, process development teams, purchasing managers, contract manufacturers, and distributors sourcing 2,4,6-Trifluorophenylboronic acid for laboratory or commercial synthesis. It is also useful for buyers comparing suppliers that offer different pack sizes, quality grades, and delivery terms. I focus on practical procurement decisions rather than treating a catalog listing as sufficient evidence of suitability.

The right purchasing decision depends on more than the chemical name. Your team should match the material specification to the reaction, assess how much analytical information is required, and confirm whether the supplier can support repeat orders. When the material is part of a regulated or customer-controlled process, documentation and change communication may be as important as the nominal price.

Basic Chemical Context

2,4,6-Trifluorophenylboronic acid contains a boronic acid functional group attached to a fluorinated aromatic ring. Its CAS Registry Number is 182482-25-3, and the molecular formula is commonly represented as C₆H₄BF₃O₂. The calculated molecular weight is approximately 175.91 g/mol, which is useful when converting between mass and molar quantities during laboratory planning.

The boronic acid group makes this compound relevant to carbon–carbon bond-forming chemistry, particularly Suzuki-type coupling applications. The three fluorine substituents can influence the electronic character and lipophilicity of the resulting aromatic fragment, but the actual reaction performance depends on the coupling partner, catalyst system, solvent, base, temperature, and work-up method. I therefore recommend treating published reaction precedent as a starting point rather than a guaranteed outcome.

Material and Specification Overview

When I prepare a quotation or technical discussion, I separate confirmed product information from buyer-specific requirements. The product name and CAS number establish the requested identity, while purity, appearance, water content, residual solvents, elemental impurities, and analytical method may need to be specified separately. If your project has a validated method, I suggest sharing the relevant acceptance criteria before finalizing the purchase.

Some buyers need a research-grade material for route screening, while others require a more tightly controlled specification for process development. These requirements should not be assumed to be interchangeable. I recommend confirming the certificate of analysis format, test items, and release criteria for the actual batch offered.

Matching the Material to the Application

Medicinal and Discovery Chemistry

In medicinal chemistry, 2,4,6-Trifluorophenylboronic acid may be selected as an aromatic coupling partner during analogue preparation. The key purchasing priorities are usually confirmed identity, consistent assay, manageable pack sizes, and rapid access to supporting documentation. For small-scale screening, a large commercial quantity may create unnecessary stock risk if the structure is later removed from the project.

Process Development and Scale-Up

Process teams generally need more than a single successful small-scale reaction. They may need repeatable quality, clear batch records, suitable packaging, and a realistic supply plan for multiple development campaigns. Before scale-up, I recommend checking whether the supplier can discuss production batch availability, sampling, analytical testing, and continuity without promising an unverified fixed lead time.

Custom Synthesis and Distribution

Contract manufacturers and distributors should evaluate both immediate availability and future replenishment. A lower unit price is not necessarily advantageous if the supplier cannot support the required pack size, export documents, or repeat-order schedule. For resale or multi-customer use, buyers should also clarify labeling, packaging configuration, shelf-life information where available, and document language requirements.

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A Practical Supplier Selection Framework

I use a five-part framework when reviewing a supplier for this product: identity, quality, logistics, communication, and commercial fit. First, confirm that the offered item is specifically 2,4,6-Trifluorophenylboronic acid with CAS 182482-25-3 rather than a similarly named isomer. Second, request the available analytical package and compare it with your internal specification.

1. Define the use case: State whether the material is for discovery research, process development, manufacturing, or distribution.
2. Set the quality requirement: Specify purity, appearance, water, residual solvent, or other tests only when they are relevant to your process.
3. Confirm quantity: Request available pack sizes and identify whether the need is a one-time order or a recurring program.
4. Review logistics: Ask for estimated lead time, shipping terms, export documentation, and packaging details.
5. Evaluate continuity: Discuss batch consistency, communication of specification changes, and the process for repeat quotations.

For a first purchase, I recommend requesting a quotation that clearly separates product price, packaging, freight, taxes where applicable, and any documentation or testing charges. This makes supplier comparisons more meaningful. It also helps your purchasing team identify whether a quote is based on available stock, scheduled production, or a future manufacturing slot.

Pricing, MOQ, and Lead-Time Considerations

Pricing for specialty organic boronic acids can vary with quantity, purity specification, packaging, analytical requirements, and delivery destination. I do not recommend relying on a generic online price because it may represent a different pack size, an indicative figure, or a non-current supply condition. A direct quotation should be based on your requested quantity and specification.

Minimum order quantity is also supplier- and production-dependent. Small research packs may be practical for route investigation, whereas process programs may justify a larger order if the material has been qualified. Lead time should be confirmed in writing because it can differ between in-stock material, repacking, quality release, and new production.

Common Procurement Mistakes

One common mistake is ordering solely by the shortened name “trifluorophenylboronic acid.” Positional isomers can have different CAS numbers and different reaction behavior, so the full name and CAS number should appear on the purchase request. Another mistake is requesting only a purity number without asking how that value was measured or what other batch information is available.

Buyers also sometimes overlook packaging and transport conditions. Boronic acids may be sensitive to moisture or handling conditions depending on their physical form and formulation, so the supplier’s storage and shipping guidance should be reviewed before receipt. Finally, a buyer should not assume that a supplier’s standard specification automatically satisfies a customer or regulatory specification.

How Maison Chemical Supports Procurement

At Maison Chemical, I support B2B inquiries by reviewing the requested identity, quantity, quality level, destination, and intended use. I can help organize a quotation for 2,4,6-Trifluorophenylboronic acid CAS 182482-25-3 and clarify which product documents are available for the offered batch. Depending on the project, the discussion may include packaging, delivery planning, repeat supply, and additional analytical requirements.

My approach is to avoid making assumptions about purity, stock status, certification, or delivery until those details have been checked for the specific order. This is particularly important when the material will enter a controlled synthesis or be resold to another organization. Buyers can improve response quality by including the target quantity, destination country, required delivery window, and any internal specification in their initial inquiry.

Key Takeaways

• Confirm the complete identity: 2,4,6-Trifluorophenylboronic acid, CAS 182482-25-3.
• Use the approximate molecular weight of 175.91 g/mol for preliminary molar calculations.
• Match purity, analytical testing, and documentation to the actual application.
• Compare MOQ, pack size, lead time, freight, and repeat-supply capability—not price alone.
• Request batch-specific information before approving the material for a critical process.

Conclusion and Next Steps

The best way to procure 2,4,6-Trifluorophenylboronic acid CAS 182482-25-3 is to combine exact identity confirmation with application-based quality requirements and realistic supply planning. For discovery work, a suitable small pack and clear analytical documentation may be the priority; for process or distribution programs, continuity, packaging, and repeat-order support deserve greater weight. The correct supplier is the one that can align these requirements with verifiable product information.

To begin, send Maison Chemical your required quantity, target specification, destination, and preferred delivery schedule. I can then help clarify the available product information, quotation basis, packaging options, and procurement pathway. This structured approach gives your team a clearer basis for evaluating the material before placing an order.

Contact us to discuss your requirements of 2,4,6-Trifluorophenylboronic acid CAS 182482-25-3. Our experienced sales team can help you identify the options that best suit your needs.